MOOSE Lab

MOOSE Lab

Machine-learning in Ophthalmology & Ocular Science Ensemble

We develop and validate machine learning methods for eye disease, from the cornea to the optic nerve, to advance human well-being through improved sight. We believe in supporting the next generation of physician-scientists, providing opportunities for trainees to work together with mentors in pursuit of new scientific knowledge.

News

Nov 2026The first MOOSE symposium brings 26 student talks to Auditorium G at Dartmouth Hitchcock Medical Center.
Oct 2026Our study of donor endothelial grading and graft failure in the Cornea Preservation Time Study is in press at Frontiers in Medicine.
Oct 2026Our work on triage of open globe injury from external eye photographs was presented at the American Medical Association Research Challenge.
Jun 2026Our open globe injury triage classifier was presented at the Second Annual Dartmouth Ophthalmology Resident/Trainee Research Conference.

Research

Cornea and eye banking

Endothelial cell counts, graft survival in CPTS, keratoconus, keratitis, corneal nerves, biomechanics.

Ocular surface

Meibomian gland and goblet cell imaging.

Retina

Diabetic retinopathy (incl. DRCR data), ROP, AMD, OCT and laser scanning images.

Glaucoma and neuro-ophthalmology

Visual field forecasting, glaucoma screening, papilledema.

Surgery, trauma and orbit

Open globe triage, endophthalmitis, PCO, orbital imaging.

Evaluating AI

How often-overlooked implementation details, such as data splits, leakage and benchmarks, change reported accuracy.

Recent publications

  1. Front Med
    Chuter B*, Joe C, Jablonski MM, Gensheimer WG. Donor endothelial grading and specular images did not measurably improve graft-failure prediction over a clinical reference in the Cornea Preservation Time Study. In press, Frontiers in Medicine. https://doi.org/10.3389/fmed.2026.1993740
  2. Chuter B*, Kayarian FB, Hassan S, Shaadab A, Shah S, Millis BR, Jablonski MM, Gensheimer WG. A mechanistic digital twin of the corneal endothelium separates early postoperative and long-term endothelial cell loss after keratoplasty. Submitted to npj Systems Biology and Applications.
  3. npj Digit Med
    Chuter B*, Kayarian FB, Kim MY, Millis BR, Mukit FA, Lee T, Chong P, Justin G, Miller T, Marshall J, Jablonski MM, Gensheimer WG*. Automated triage of open globe injury from external-eye photographs for low-resource settings. Submitted to npj Digital Medicine.
  4. TVST
    Chuter B*, Kayarian FB, Mondragon A, Daley T, Jablonski MM, Gensheimer WG. Fitting Each Patient’s Own Decay Curve Outperforms a Neural Operator Across Most Weightings for Corneal Endothelial Cell Density Forecasting. Submitted to Translational Vision Science & Technology.

All publications